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Futures in Biotech 37: Just A Touch Of Green

Futures in Biotech

Hosts: Marc Pelletier and Dr. Glen Ernstrom Guest: Marty Chalfie, 2008 Nobel Laureate in Chemistry This episode covers how Marty Chalfie discovered the molecular machinery that senses touch. In Part II, Chalfie describes how he developed one of the most important tools of modern molecular biology, one that allows us to see inside a living cells, down to the protein level. With green fluorescent protein, or GFP, we can now track the life of a protein, from when the gene that makes the protein is turned on, to where it goes, to where it dies. Audible Pick: The Snows of Kilimanjaro and Other Stories, Abridged, By Ernest Hemingway, Narrated by Stacy Keach. Transcripts to the shows are now available on the FiB Extras blog thanks tom.price@podsinprint.com, PodsinPrint Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 57:56 read less

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Futures in Biotech 37: Just A Touch Of Green

Mon December 29 2008

Hosts: Marc Pelletier and Dr. Glen Ernstrom Guest: Marty Chalfie, 2008 Nobel Laureate in Chemistry This episode covers how Marty Chalfie discovered th... read more

Futures in Biotech 36: Avoiding Death, Not Taxes with Dr. Cynthia Kenyon

Mon November 24 2008

Host: Marc Pelletier Guest: Dr. Cynthia Kenyon; Professor, Department of Biochemistry and Biophysics, University of California San Francisco, Director... read more

Host: Marc Pelletier Guest: Dr. Cynthia Kenyon; Professor, Department of Biochemistry and Biophysics, University of California San Francisco, Director of the Larry L. Hillblom Center for the Biology of Aging. We are back into a world leading lab to discuss the genetics of aging. Can it be controlled? You bet, and the implications are enormous. When these findings translate to the clinic, it will truly be a game changer for humanity. Some interesting links: sirtrispharma Elixir Sirtris Audible Pick: Prey by Michael Crichton. For a 30 day free trial visit GotoMeeting Transcripts to the shows are now available on the FiB Extras blog thanks tom.price@podsinprint.com, PodsinPrint Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 1:01:21 read less

Futures in Biotech 35: The Brain Machine Interface

Mon October 27 2008

Host: Marc Pelletier Dr. Justin Sanchez discusses technologies that enable direct brain to computer interfacing, just think… Guest: Dr. Justin ... read more

Host: Marc Pelletier Dr. Justin Sanchez discusses technologies that enable direct brain to computer interfacing, just think… Guest: Dr. Justin C. Sanchez, Director of the Neuroprosthetics Research Group, Assistant Professor, Department of Pediatrics, Division of Neurology, Department of Neuroscience, Department of Biomedical Engineering, University of Florida. I really had no idea that the technologies that Justin has developed existed other than in science fiction. The possibilities are endless, and could change everything from computing, to flying planes, to simply changing the channel… I will keep these notes short, and let Justin explain. Find more, including videos at: The Neuroprosthetics Research Group Transcripts to the shows are now available on the FiB Extras blog thanks tom.price@podsinprint.com, PodsinPrint. Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 50:11 read less

Futures in Biotech 34: A Great Historical Document - The Human Genome

Fri September 12 2008

Host: Marc Pelletier Mark Gerstein endeavors to make sense our genome on its past and present course. Guest: Mark Gerstein, the Albert L. Williams Pro... read more

Host: Marc Pelletier Mark Gerstein endeavors to make sense our genome on its past and present course. Guest: Mark Gerstein, the Albert L. Williams Professor of Biomedical Informatics, a professor of Molecular Biophysics and Biochemistry and professor of Computer Science at Yale University Gerstein Lab. In past shows, we've had Lee hood, the inventor of the DNA sequencer, and George Church who was among those personally involved in initiating the Human project. But getting the code and really understanding these human blueprints are entirely different problems. Our guest today, Mark Gerstein, is trying to make sense of it all, and his work amoung other things has revealed that the genome is more than just a blueprint, or list of parts, but a rich historical text about our past. BLAST this sequence: atgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaa Instructions: Copy and Paste the DNA sequence into the query window, and hit the blast button. What does this encode? Interesting: Try again selecting the NON-HUMAN database. What organism is the exact same gene found in? Why? Audible pick of the week: Legacy of Ashes: The History of the CIA, Unabridged, By Tim Weiner, Narrated by Stefan Rudnicki. For your free audio book visit Audible.com/biotech. TWiT T-Shirts from Lori LeBeau Walsh. Transcripts to the shows are now available on the FiB Blog thanks to the kind folks at PodsinPrint. Also thanks to Philippe Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 55:35 read less

Futures in Biotech 33: Dr. Milner’s Explorations Into The Human Mind

Wed July 23 2008

Host: Marc Pelletier Dr. Brenda Milner describes the experiments that led to a revolution in modern neuroscience. Guest: Dr. Brenda Milner; Dorothy J.... read more

Host: Marc Pelletier Dr. Brenda Milner describes the experiments that led to a revolution in modern neuroscience. Guest: Dr. Brenda Milner; Dorothy J. Killam Professor of Psychology, Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada. Throughout her 58 years at the Montreal Neurological Institute, Dr. Milner has explored the inner workings of the human mind, and helped define the structures that give us our exquisite memory and ability for leaning. Her groundbreaking work has influenced generations of psychologists and neuroscientists, and through her unbridled curiosity has revealed many facets to the human mind that were previously unknown. Gairdner Foundation Gairdner News Dr. Milner on Wikipedia Audible pick of the week: Starswarm by Dr. Jerry Pournelle, narrated by Lloyd James. For your free audio book visit Audible.com/biotech. Transcripts to the shows are now available on the FiB Blog thanks to the kind folks at PodsinPrint. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 1:12:37 read less